A mole is a unit of measurement used in chemistry to express the amount of a substance. Specifically, a mole is defined as the amount of a substance that contains the same number of particles (such as atoms, molecules, or ions) as there are in 12 grams of carbon-12. This number, known as Avogadro’s number, is approximately 6.02 x 10^23 particles per mole.
Therefore, the statement that best describes a mole is that it is a unit of measurement used in chemistry to express the amount of a substance.